Losartan Impurities

Losartan is an angiotensin II receptor blocker (ARB) primarily used to treat hypertension and diabetic nephropathy, a kidney condition associated with diabetes. By blocking the effects of angiotensin II, it helps relax blood vessels, reduce blood pressure, and protect kidney function. Losartan is also prescribed to reduce the risk of stroke in patients with high blood pressure and heart enlargement. In pharmaceutical production, ensuring the purity of Losartan is critical for its efficacy and patient safety. Impurity profiling is essential during its synthesis to detect and quantify potential contaminants or by-products, ensuring the drug meets strict regulatory standards. Impurity analysis helps prevent adverse effects and ensures the drug's therapeutic effectiveness.