Abstract
CJC-1295 is a synthetic analog of growth hormone-releasing hormone or growth hormone-releasing factor, and a growth hormone pro-secretory agent. Invented by a Canadian biotechnology company called ConjuChem, CJC-1295 is a synthetic peptide that, like other peptides, consists of 30 amino acids and resembles a protein.
What is CJC-1295?
CJC-1295 is a popular supplement that helps increase growth hormone levels in the body. Optimizing these levels can help muscle growth, improve muscle mass, and boost the body's energy and metabolism.CJC-1295 helps stimulate the release of GH into the bloodstream through its effect on the pituitary gland. This achieves higher levels than naturally produced products. Subsequently, when GH levels increase, the liver produces IGF-1 (insulin-like growth factor 1). Increased IGF-1 can lead to faster muscle development and other physical benefits such as endurance, cellular and skeletal muscle repair, and shorter recovery times.
Two types of CJC 1295 :
GHRH (growth hormone-releasing hormone) is produced in the hypothalamus. Its pulsed release from the hypothalamus triggers the pulsed release of GH in the pituitary gland. the half-life of GHRH is very short, only a few minutes (half-life = the time it takes to remove half of the substance from the blood. The shorter the half-life, the faster the substance is removed from the body and the less it affects the body).
The first 29 amino acids of GHRH are the active region. They are provided in the form of the artificial peptide Sermorelin. Sermorelin is further modified to extend its half-life to 30 minutes. This is called CJC 1295. CJC-1295 is further modified by adding DAC (drug affinity complex) to it. DAC binds to a blood protein called albumin, which extends its half-life to 8 days. The longer half-life of DAC-bound albumin means that injections are only needed once or twice a week. However, the long half-life and relatively constant blood levels provide a constant stimulus for GH release from the pituitary through the GHRH receptor, which is not physiologic. This could reduce GH pulse amplitude, which would result in reduced GH tissue stimulation.
Why should I use CJC-1295?
First, CJC has long-lasting effects. Usually, the endogenous growth hormone level in the body can be increased for more than 6 days after a single injection of CJC, while the boost of IGF-1 is amplified to about 10 days. The peak serum level of IGF-1 can last for up to one month with multiple injections.
Secondly, the superposition of CJC with other peptides prolongs the duration of the action of other peptide hormones. when CJC is superimposed with other peptides, covalent bonds are formed between their molecules, and this interlocking reaction will greatly prolong the duration of action of other peptides remaining in the body, thus prolonging their effect on the muscle.
Moreover, CJC has a promoting and maintaining effect on the pituitary gland. The pituitary gland, as the most important and complex endocrine gland in the human body, will also continue to degenerate with age, and the secretion of the growth hormone HGH will be less and less fluid. And the use of CJC can slow down the aging of the pituitary gland, and maintain the level of growth hormone secretion in the body, while both muscle gain and fat loss have a fairly good promotion effect.
Finally, CJC is also the king of peptide fat loss. In terms of fat loss, CJC-1295 is very effective, not only to promote its growth hormone secretion can also promote insulin growth factor secretion and thyroid secretion because CJC is to promote the secretion of endogenous growth hormone so will not inhibit the secretion of endogenous growth hormone-like HGH, CJC-1295 can better increase the level of thyroid hormone in the body, which makes its fat loss effect is far more than CJC-1295 can increase the level of thyroid hormone in the body, which makes its effect of fat loss far more than that of growth hormone (HGH). Burning fat while growing muscle is certainly the most important result we want to see. The peptide hormone with the strongest fat-loss ability is CJC1295, and CJC-1295 is also suitable for female fat loss.
What are the side effects of CJC-1295?
Like many other compounds, when taking CJC-1295, your body needs time to get used to the substance, which means that the potential side effects are mild in nature. Of course, they will usually dissipate as your body gets used to the compounds. Some side effects include headaches, dizziness, nausea, fatigue, or flushing.
In rare cases, allergic reactions may occur. Symptoms of such reactions usually include hives or difficulty swallowing. If any symptoms persist or worsen, it is best to seek immediate medical attention.
Summary
Scientists have now found that CJC-1295 is very effective in increasing growth hormone secretion and IGF-1 without negatively affecting the pulsation of GH secretion. The primary use of CJC-1295 is to provide increased levels of GH, which also leads to increased levels of IGF-1. These increased levels can help with fat loss and in some cases can help with muscle gain. Typically, CJC-1295 is used in combination with Ipamorelin because of its enhanced specificity as a growth hormone-releasing hormone.CJC-1295 is a growth hormone-releasing hormone mimetic or analog. That is, it works in the same way as GHRH and can be referred to as GHRH.
As far as the typical use of CJC-1295 is concerned, it is currently being investigated as a treatment for growth hormone deficiency. In addition to this, it is also seen as a treatment for lipodystrophy. Lipodystrophy is a condition in which the body is unable to produce and maintain healthy adipose tissue.
When children are treated with growth hormone-releasing hormones, growth hormone deficiency responds quite well to these treatments. However, this treatment is practically unsustainable due to its half-life. However, with CJC-1295, the half-life is extended, giving way to more potentiation.