Isotope Labeled Bile Acids

Isotope-labeled bile acids are bile acids containing stable isotopes like carbon-13 or deuterium. They are used in research to study bile acid metabolism, transport, and signaling. Bile acids are important for fat digestion and absorption, and their imbalance is linked to various diseases. By introducing isotope-labeled bile acids into biological systems, researchers can track their movement and metabolism, studying synthesis, secretion, and reabsorption in the intestine and liver. Isotope-labeled bile acids are particularly useful in studying bile acid-related diseases such as cholestasis, gallstone formation, and liver diseases. They provide insights into disease mechanisms and can aid in developing diagnostic and therapeutic strategies targeting bile acid metabolism.