In vivo Formulation Calculator(Clear solution)
Step 1:Enter information below(Recommended:An additional animal making an allowance for loss during the experiment)
Step 2:Enter the in vivo formulation.
Calculation results:
Working concentration:mg/ml;
Method for preparing DMSO master liquid:mg drug pre-dissolved inμL DMSO(Master liquid concentrationmg/mL
Method for preparing in vivo formulation:TakeμL DMSO master liquid,next addμL PEG300,mix and clarify,next addμL Tween 80,mix and clarify,next addμL ddH2O,mix and clarify.
Method for preparing in vivo formulation:TakeμL DMSO master liquid,next addμL Corn oil,mix and clarify.
Note:1.Please make sure the liquid is clear before adding the next solvent.
2.Be sure to add the solvent(s)in order.You must ensure that the solution obtained,in the previous addition,is a clear solution before proceeding to add the next solvent.Physical methods such
as vortex,ultrasound or hot water bath can be used to aid dissolving.