CMV

Cytomegalovirus (CMV) is a member of the herpesvirus family, widespread in the human population, and typically remains dormant in the body after initial infection. It can cause severe disease in newborns and immunocompromised individuals, including transplant recipients and HIV/AIDS patients. CMV primarily targets epithelial cells, endothelial cells, and leukocytes, and it can establish lifelong latency with periodic reactivation. Targeting CMV therapeutically involves antiviral drugs that inhibit viral replication enzymes or prevent the virus from entering cells. Research also focuses on developing vaccines to prevent CMV infection. As CMV can lead to serious complications, such as congenital disabilities, retinitis, and organ damage, effective management and therapeutic strategies are critical.