HCV Protease

Hepatitis C virus (HCV) protease is a critical enzyme that plays a key role in the lifecycle of the hepatitis C virus by processing the viral polyprotein into functional units necessary for viral replication. This enzyme, specifically known as NS3/4A serine protease, cleaves the HCV polyprotein at multiple sites, enabling the maturation of the virus. Due to its essential role in the replication and survival of the virus, HCV protease is a prime target for antiviral drugs. Inhibitors of this protease have been developed and are used as a part of combination therapies to effectively manage and treat HCV infections, offering hope for curing patients with this chronic disease.