Benzodiazepines

Benzodiazepines (BZDs) are a class of psychoactive drugs that act on the central nervous system and can be used in various clinical treatments. In the body, they can rapidly diffuse through the blood-brain barrier and act on the complex of GABA receptors, benzodiazepine receptors, and chloride channels. By enhancing the activity of GABA, BZDs further open the chloride channels and impel a large number of chloride ions to enter the cells and cause hyperpolarization of nerve cells, thus playing a central inhibitory role and further exerting sedative-hypnotic, anxiolytic, and anticonvulsant effects.