Dynamin

Dynamins are a family of GTPase enzymes crucial for cellular processes involving membrane remodeling, such as endocytosis and vesicle trafficking. Dynamins play a pivotal role in the "pinching off" process of vesicles from membranes, which is essential for the internalization of nutrients, signaling molecules, and receptors from the cell surface to the interior. They are also involved in other cellular activities like cytokinesis and organelle division. Given their fundamental role in cellular homeostasis and communication, dysfunctions in dynamins are linked to various neurological disorders and impaired cellular growth and development. Therefore, targeting dynamins offers potential therapeutic strategies for diseases related to vesicle trafficking and membrane dynamics.