5-HT Receptor

The 5-HT receptor, or serotonin receptor, encompasses a group of G protein-coupled receptors and ligand-gated ion channels found in the central and peripheral nervous systems. They mediate the effects of serotonin, a key neurotransmitter involved in numerous physiological processes, including mood regulation, appetite, sleep, memory, and learning. These receptors are categorized into several classes and subtypes, such as 5-HT1, 5-HT2, and others, each having distinct roles and signaling mechanisms. Due to their central role in neurotransmission, 5-HT receptors are prime targets for therapeutic drugs used to treat various psychiatric and neurological conditions, such as depression, anxiety, migraine, and schizophrenia. Modulating these receptors can help correct dysregulated serotonin levels, offering potential relief from these disorders.