Neuropeptide Y Receptor

Neuropeptide Y (NPY) receptors are a group of receptors in the human body that bind to Neuropeptide Y, a 36-amino acid peptide neurotransmitter extensively distributed throughout the central and peripheral nervous systems. These receptors are crucial for a variety of physiological processes, including regulating food intake, energy balance, anxiety, stress response, and circadian rhythms. NPY receptors belong to the G protein-coupled receptor (GPCR) family, and there are several subtypes, including Y1, Y2, Y4, Y5, and Y6, each with distinct roles and tissue distribution. The activation of these receptors by NPY can influence cardiovascular functions, neuroendocrine secretion, and even cell growth, making them significant targets in obesity and anxiety disorder treatments.