Vasopressin Receptor

Vasopressin receptors are a group of G-protein coupled receptors that specifically bind to vasopressin, a key hormone involved in maintaining water balance and vasoconstriction. These receptors are primarily located in the kidneys, vascular smooth muscle cells, and brain. There are three main types: V1A, V1B, and V2. The V1A receptor mediates vasoconstriction and influences social behaviors, the V1B receptor is involved in stress responses, and the V2 receptor functions in the kidneys to regulate water reabsorption. Activation of these receptors by vasopressin leads to various effects, including increased water retention, elevated blood pressure, and changes in social and sexual behaviors, highlighting their critical role in both physiological and behavioral regulation.