GABA Receptor

The GABA receptor, specifically known as the Gamma-Aminobutyric Acid receptor, plays a crucial role in the nervous system as the primary inhibitory neurotransmitter receptor. It functions by responding to GABA neurotransmitter signals, facilitating a decrease in neuronal excitability across the nervous system. This process is essential for maintaining a balance between neuronal stimulation and inhibition, crucial for preventing overexcitation that can lead to disorders like epilepsy. GABA receptors are classified mainly into two types: GABA_A receptors, which are ionotropic and promote fast synaptic inhibition, and GABA_B receptors, which are metabotropic, affecting slow inhibitory signals. Their modulation is a key target in pharmacology for treating various neurological conditions.