Factor Xa

Factor Xa is a critical enzyme in the coagulation cascade, responsible for the conversion of prothrombin to thrombin, which ultimately leads to the formation of a blood clot. As a key component of the blood coagulation pathway, Factor Xa functions at the convergence point of the intrinsic and extrinsic pathways, making it a pivotal player in hemostasis. Due to its central role in clot formation, Factor Xa is a prime target for anticoagulant drugs. Inhibitors of Factor Xa, such as rivaroxaban and apixaban, are used to prevent and treat thrombosis, reducing the risk of stroke, deep vein thrombosis, and pulmonary embolism in patients with atrial fibrillation or following major orthopedic surgery.