Stearoyl-CoA Desaturase (SCD)

Stearoyl-CoA Desaturase (SCD) is a key enzyme in lipid metabolism that catalyzes the synthesis of monounsaturated fats from saturated fatty acids. SCD primarily converts stearoyl-CoA and palmitoyl-CoA into oleoyl-CoA and palmitoyl-CoA, respectively. These monounsaturated fats are crucial components of cell membranes and are involved in processes such as fluidity regulation and signal transduction. SCD activity is essential for producing fats that serve as energy reserves and signaling molecules. Dysregulation of SCD is linked to various metabolic disorders, including obesity, insulin resistance, and cardiovascular disease. Consequently, SCD is a potential target for drugs aimed at treating metabolic syndrome and related conditions by modulating lipid profiles and metabolic pathways.