Phosphodiesterase (PDE)

Phosphodiesterase inhibitors are key compounds in cardiovascular and pulmonary research, regulating cyclic nucleotide levels in cells. By modulating the activity of phosphodiesterase enzymes, these inhibitors help in the study of various conditions, including heart failure, pulmonary hypertension, and ischemic heart disease. Our collection includes selective PDE inhibitors, such as PDE3 and PDE5 inhibitors, which control intracellular signaling pathways related to muscle relaxation, vasodilation, and myocardial function. These inhibitors are widely used to explore cardiovascular physiology, particularly in smooth muscle relaxation and cellular communication. With applications in therapeutic research and drug development, PDE inhibitors aid in revealing new insights into cardiovascular disease mechanisms and treatment possibilities. Our products are ideal for scientists aiming to advance research in cardiovascular dysfunction and develop effective therapies for heart conditions, pulmonary diseases, and stroke prevention.