(±)-Bisoprolol hemifumarate

• CAT Number: I000247
• CAS Number: 104344-23-2
• Molecular Formula: C22H35NO8
• Molecular Weight: 441.52
• Purity: ≥95%
• Synonyms: (E)-but-2-enedioic acid;1-(propan-2-ylamino)-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]propan-2-ol
• Target: Adrenergic Receptor
• Solubility: DMSO 88 mg/mLWater 88 mg/mLEthanol 88 mg/mL
• Storage: 3 years -20℃ powder
• IUPAC Name: [2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydrochromen-6-yl] acetate
• InChI: InChI=1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3
• InChIKey: ZAKOWWREFLAJOT-UHFFFAOYSA-N
• SMILES: CC1=C(C(=C(C2=C1OC(CC2)(C)CCCC(C)CCCC(C)CCCC(C)C)C)OC(=O)C)C

(±)-Bisoprolol hemifumarate (Cat.No: I000247) is a medication used to treat hypertension and certain types of heart failure. It works by blocking beta-adrenergic receptors in the heart, leading to a decrease in heart rate and blood pressure. This white or off-white crystalline powder is typically administered orally in tablet form and may have side effects, such as fatigue and dizziness.

Reference

[1]. Matsui, S., et al., Protective effect of bisoprolol on beta-1 adrenoceptor peptide-induced autoimmune myocardial damage in rabbits. Herz, 2000. 25(3): p. 267-70.
[2]. Wargon, M., et al., Acute effects of bisoprolol on respiratory sinus arrhythmia. Fundam Clin Pharmacol, 1998. 12(4): p. 451-6.