For research use only. Not for therapeutic Use.
Highly potent Nicotinic agonist, Analgesic, Non-Narcotic.The enantiopure (+)-Epibatidine (Axon 1077) and (-)-Epibatidine (Axon 1078) are available as well.
KEYWORDS: (±)-Epibatidine dihydrochloride | supplier | Nicotinic agonist | Epibatidine HCl | CAS [162885-01-0] | [148152-66-3] | Acetylcholine | nAChR | Agonist | Ion Channel | Nicotine | receptor | Analgesic | Non-Narcotic
| Catalog Number | I047480 |
| CAS Number | 162885-01-0 |
| Molecular Formula | C11H13ClN2.2HCl |
| Purity | ≥95% |
| IUPAC Name | (1S,2S,4R)-2-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane;dihydrochloride |
| InChI | InChI=1S/C11H13ClN2.2ClH/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8;;/h1,4,6,8-10,14H,2-3,5H2;2*1H/t8-,9+,10+;;/m1../s1 |
| SMILES | C1C[C@H]2[C@@H](C[C@@H]1N2)C3=CN=C(C=C3)Cl.Cl.Cl |
| Reference | F Lembeck. Epibatidine: high potency and broad spectrum activity on neuronal and neuromuscular nicotinic acetylcholine receptors. Naunyn Schmiedebergs Arch. Pharmacol. 1999, 359, 378-385.
MW Decker and MD Meyer. Therapeutic potential of neuronal nicotinic acetylcholine receptor agonists as novel analgesics. Biochem. Pharmacol. 1999, 58, 917-923.
B. Badio et al. Epibatidine, a potent analgetic and nicotinic agonist. Mol. Pharmacol. 1994, 45, 563-569. |
