For research use only. Not for therapeutic Use.
(±)-Epinephrine is a natural neurotransmitter that is released from the adrenal medulla and activates adrenoceptors (K<sub>i</sub>s = 15, 735, and 3,970 nM for α<sub>1A-</sub>, β<sub>2-</sub>, and β<sub>1-</sub>adrenergic receptors, respectively). Through these receptors, (±)-epinephrine may induce either contraction or relaxation of vascular smooth muscle, depending on adrenoceptor subtype expression. Receptor-mediated actions of (±)-epinephrine are also relevant to blocking anaphylaxis, reversing cardiac arrest, and reducing bleeding in clinical trials.
| CAS Number | 329-63-5 |
| Synonyms | (±)-Adrenaline;DL-Adrenaline;DL-Epinephrine |
| Molecular Formula | C9H14ClNO3 |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol;hydrochloride |
| InChI | InChI=1S/C9H13NO3.ClH/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;/h2-4,9-13H,5H2,1H3;1H |
| InChIKey | ATADHKWKHYVBTJ-UHFFFAOYSA-N |
| SMILES | CNCC(C1=CC(=C(C=C1)O)O)O.Cl |
| Reference | 1.Rothman, R.B.,Vu, N.,Partilla, J.S., et al. In vitro characterization of ephedrine-related stereoisomers at biogenic amine transporters and the receptorome reveals selective actions as norepinephrine transporter substrates. J. Pharmacol. Exp. Ther. 307( |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
