For research use only. Not for therapeutic Use.
β-Elemonic acid is a triterpene isolated from <em>Boswellia</em> (<em>Burseraceae</em>) that exhibits anticancer activity. It inhibits growth of non-small cell lung cancer (NSCLC) A549 cells (IC<sub>50</sub> = 6.92 µM) <em>in vitro</em>. β-Elemonic acid induces apoptosis and cytotoxicity in A549 cells in a dose-dependent manner but has no effect on normal epithelial WI-38 cells. It inhibits phosphorylation of p42/44, MAPK/JNK, and p38 and induces production of reactive oxygen species (ROS) and COX-2 expression <em>in vitro</em>. β-Elemonic acid also inhibits prolyl endopeptidase (IC<sub>50</sub> = 39.74 µM) <em>in vitro</em>.
| Catalog Number | R060826 |
| CAS Number | 28282-25-9 |
| Synonyms | 3-oxo-(13α, |
| Purity | ≥95% |
| Storage | -20°C |
| Reference | 1.Atta-ur-Rahman,Naz, H.,Fadimatou, et al. Bioactive constituents from Boswellia papyrifera. J. Biol. Chem. 68(2), 189-193 (2005). |
