γ1-MSH

For research use only. Not for therapeutic Use.

  • CAT Number: P000227
  • CAS Number: 72629-65-3
  • Molecular Formula: C72H97N21O14S
  • Molecular Weight: 1512.761
  • Purity: ≥95%
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Endogenous melanocortin MC<sub>3</sub> receptor agonist (pK<sub>i</sub> = 7.46) that displays ~ 40-fold selectivity over MC<sub>4</sub>. Increases the release of extracellular dopamine, which induces grooming and vertical activity (rearing) in rats. Exhibits hypertensive, tachycardic and short-term analgesic activity <em>in vivo</em>.


Catalog Number P000227
CAS Number 72629-65-3
Molecular Formula C72H97N21O14S
Purity ≥95%
Target Melanocortin (MC) Receptors
Solubility Soluble to 1 mg/ml in 20% acetonitrile / water
Storage Store at -20C
InChI InChI=1S/C72H97N21O14S/c1-40(2)60(93-62(99)48(73)30-43-22-24-46(94)25-23-43)70(107)88-52(26-29-108-3)63(100)83-38-58(95)85-56(34-45-37-79-39-84-45)68(105)90-54(32-42-16-8-5-9-17-42)66(103)86-51(21-13-28-81-72(77)78)65(102)91-55(33-44-36-82-49-19-11-10-18-47(44)49)67(104)92-57(35-59(96)97)69(106)87-50(20-12-27-80-71(75)76)64(101)89-53(61(74)98)31-41-14-6-4-7-15-41/h4-11,14-19,22-25,36-37,39-40,48,50-57,60,82,94H,12-13,20-21,26-35,38,73H2,1-3H3,(H2,74,98)(H,79,84)(H,83,100)(H,85,95)(H,86,103)(H,87,106)(H,88,107)(H,89,101)(H,90,105)(H,91,102)(H,92,104)(H,93,99)(H,96,97)(H4,75,76,80)(H4,77,78,81)/t48-,50-,51-,52-,53-,54-,55-,56-,57-,60-/m0/s1
InChIKey SLEIICTWQFRIFM-SLNSXFHGSA-N
SMILES CC(C)C(C(=O)NC(CCSC)C(=O)NCC(=O)NC(CC1=CNC=N1)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(CC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC5=CC=CC=C5)C(=O)N)NC(=O)C(CC6=CC=C(C=C6)O)N

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