Δ12-Prostaglandin J2 Lipid Maps® MS Standard

• CAT Number: R015421
• CAS Number: 87893-54-7
• Molecular Formula: C20H30O4
• Molecular Weight: 334.5
• Purity: ≥95%
• Synonyms: Δ12-PGJ2
• Target: Apoptosis
• Storage: -80°C
• InChI: 1S/C20H30O4/c1-2-3-6-10-17(21)13-14-18-16(12-15-19(18)22)9-7-4-5-8-11-20(23)24/h4,7,12,14-17,21H,2-3,5-6,8-11,13H2,1H3,(H,23,24)/b7-4-,18-14+/t16-,17-/m0/s1
• InChIKey: TUXFWOHFPFBNEJ-GJGHEGAFSA-N
• SMILES: CCCCC[C@@H](C/C=C/1\[C@H](C=CC1=O)C/C=C\CCCC(=O)O)O

Δ12-Prostaglandin J2 is a bioactive lipid derived from prostaglandin D2 through dehydration. It is known for its anti-inflammatory and immunomodulatory properties, acting as a natural ligand for peroxisome proliferator-activated receptor gamma (PPARγ), which regulates gene expression involved in inflammation and metabolism. As a Lipid Maps® MS Standard, it serves as a reference compound for mass spectrometry, ensuring accurate identification and quantification of lipid molecules in research. This standard is essential for studying lipid signaling pathways, oxidative stress responses, and various metabolic processes, making it a critical tool in biochemical and pharmaceutical research.

Reference

1.Fitzpatrick, F.A., and Wynalda, M.A. Albumin-catalyzed metabolism of prostaglandin D2. Identification of products formed in vitro. The Journal of Biological Chemisty 258, 11713-11718 (1983).