∆6-Fulvestrant

• CAT Number: C000790
• CAS Number: 2170200-14-1
• Molecular Formula: C₃₂H₄₅F₅O₃S
• Molecular Weight: 604.76
• Purity: ≥95%
• Synonyms: 7-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10),6-tetraene-3,17β-diol; Fulvestrant Impurity E
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• Appearance: Off-White to Pale Yellow Solid
• Storage: -20°C
• IUPAC Name: (8R,9S,13S,14S,17S)-13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]-8,9,11,12,14,15,16,17-octahydrocyclopenta[a]phenanthrene-3,17-diol
• InChI: InChI=1S/C32H45F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,20-21,26-29,38-39H,2-10,13-19H2,1H3/t26-,27+,28+,29-,30+,41?/m1/s1
• InChIKey: NKMFFYOPQZINKX-IGFVOJFVSA-N
• SMILES: CC12CCC3C(C1CCC2O)C(=CC4=C3C=CC(=C4)O)CCCCCCCCCS(=O)CCCC(C(F)(F)F)(F)F

6-Fulvestrant (Cat No.:C000790) is a chemical derivative of fulvestrant, a selective estrogen receptor degrader (SERD) used in hormone receptor-positive breast cancer therapy. This compound likely holds significance in oncology research. Its unique structure suggests potential modifications to enhance drug properties. Researchers may study its interactions with estrogen receptors and its impact on receptor degradation, aiming to develop more effective treatments. Investigations into its pharmacological effects and receptor binding may contribute to optimizing SERD therapies, offering improved options for patients with hormone-responsive breast cancer by disrupting estrogen signaling and inhibiting tumor growth.