(±)8(9)-EET Lipid Maps® MS Standard

• CAT Number: R016238
• Molecular Formula: C20H32O3
• Molecular Weight: 320.5
• Purity: ≥95%
• Synonyms: (±)8,9-EpETrE
• Storage: -20°C
• InChI: InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-9-12-15-18-19(23-18)16-13-10-11-14-17-20(21)22/h6-7,9-10,12-13,18-19H,2-5,8,11,14-17H2,1H3,(H,21,22)/b7-6-,12-9-,13-10-/t18-,19+/m1/s1
• InChIKey: DBWQSCSXHFNTMO-ZZMPYBMWSA-N
• SMILES: CCCCC/C=CC/C=CC[C@@H](O1)[C@@H]1C/C=CCCCC(O)=O

(±)8(9)-<wbr></wbr>EET is biosynthesized in rat and rabbit liver microsomes by cytochrome P450. (±)8(9)-<wbr></wbr>EET is a major P450 metabolite in the renal cortex. (±)8(9)-<wbr></wbr>EET reduces the glomerular filtration rate through cyclooxygenase-<wbr></wbr>dependent preglomerular vasoconstriction.

Reference

1.Chacos, N.,Falck, J.R.,Wixtrom, C., et al. Novel epoxides formed during the liver cytochrome P-450 oxidation of arachidonic acid. Biochemical and Biophysical Research Communications 104, 916-922 (1982).