(-)-α-Benidipine Hydrochloride

• CAT Number: R048461
• CAS Number: 129262-07-3
• Molecular Formula: C28H32ClN3O6
• Molecular Weight: 542.029
• Purity: ≥95%
• Synonyms: (4R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl 5-[(3R)-1-(Phenylmethyl)-3-piperidinyl] Ester Monohydrochloride; R-(R*,R*)]- 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid Methyl 1-(Phe
• Storage: -20°C
• IUPAC Name: 5-O-[(3R)-1-benzylpiperidin-3-yl] 3-O-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydrochloride
• InChI: InChI=1S/C28H31N3O6.ClH/c1-18-24(27(32)36-3)26(21-11-7-12-22(15-21)31(34)35)25(19(2)29-18)28(33)37-23-13-8-14-30(17-23)16-20-9-5-4-6-10-20;/h4-7,9-12,15,23,26,29H,8,13-14,16-17H2,1-3H3;1H/t23-,26-;/m1./s1
• InChIKey: KILKDKRQBYMKQX-MIPPOABVSA-N
• SMILES: CC1=C(C(C(=C(N1)C)C(=O)OC2CCCN(C2)CC3=CC=CC=C3)C4=CC(=CC=C4)[N+](=O)[O-])C(=O)OC.Cl

(-)-α-Benidipine hydrochloride is a calcium channel blocker used in the treatment of hypertension and angina pectoris. It inhibits the influx of calcium ions into smooth muscle cells, leading to vasodilation and reduced blood pressure. (-)-α-Benidipine hydrochloride is a highly selective dihydropyridine calcium channel antagonist with prolonged duration of action. Research on this compound focuses on its cardiovascular effects, pharmacokinetics, and potential applications in managing cardiovascular diseases.