For research use only. Not for therapeutic Use.
α-Cholestane（Cat No.:R055417）, is a naturally occurring organic compound classified as a triterpene. It is a saturated hydrocarbon and one of the core structures in the biosynthesis of steroids in plants and animals, serving as a precursor to various important steroidal compounds like cholesterol and hormones. Cholestane’s structural simplicity makes it a valuable molecule for studying the biosynthesis of more complex steroids. It plays a fundamental role in the regulation of cellular processes and is essential for the proper functioning of living organisms.
| Catalog Number | R055417 |
| CAS Number | 481-21-0 |
| Synonyms | (5α)-Cholestane; (20R)-5α(H),14α(H),17α(H)-Cholestane; (20R)-5α(H),14α(H),17α(H)-Cholestane; 28,29,30-Trinorlanostane; Cholestane; NSC 224419; |
| Molecular Formula | C27H48 |
| Purity | ≥95% |
| Storage | room temp |
| IUPAC Name | (5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene |
| InChI | InChI=1S/C27H48/c1-19(2)9-8-10-20(3)23-14-15-24-22-13-12-21-11-6-7-17-26(21,4)25(22)16-18-27(23,24)5/h19-25H,6-18H2,1-5H3/t20-,21-,22+,23-,24+,25+,26+,27-/m1/s1 |
| InChIKey | XIIAYQZJNBULGD-XWLABEFZSA-N |
| SMILES | CC(C)CCCC(C)C1CCC2C1(CCC3C2CCC4C3(CCCC4)C)C |
| Reference | <br>1. R. Iborra et al. “Advanced Glycation in macrophages induces intracellular accumulation of 7-ketocholesterol and total sterols by decreasing the expressionof ABCA-1 and ABCG-1” Lipids in Health and Disease, vol. 10 pp. 1-7, 2011<br>2. R. Ostlund et al. “Phytosterols that are naturally present in commercial corn oil significantly reduce cholesterol absorption in humans” Am J Clin Nutr,Vol. 75(6) pp. 1000-1004, 2002<br>3. A. de Jong, J. Plat, R. Mensink “Metabolic effects of plant sterols and stanols (Review)” Journal of Nutritional Biochemistry, Vol. 14:7 pp. 362-369, 2003</br></br></br> |
