β-Amyloid (1-15)

For research use only. Not for therapeutic Use.

  • CAT Number: M045001
  • CAS Number: 183745-81-5
  • Molecular Formula: C78H107N25O27
  • Molecular Weight: 1826.84
  • Purity: ≥95%
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β-Amyloid (1-15) is a fragment of β-Amyloid peptide. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer’s disease (AD) patients.
β-Amyloid (1-15) is produced by concerted β- and α-secretase cleavage of amyloid-β protein precursor (AβPP). β-Amyloid (1-15) seems to be a sensitive acute pharmacodynamic biomarker for γ-secretase inhibition and may have several advantages compared to measuring longer CSF Aβ species. [1].


Catalog Number M045001
CAS Number 183745-81-5
Molecular Formula C78H107N25O27
Purity ≥95%
Reference

[1]. Portelius E, et al. Amyloid-β(1-15/16) as a marker for γ-secretase inhibition in Alzheimer’s disease. J Alzheimers Dis. 2012;31(2):335-41.
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