β-Endorphin, equine TFA

• CAT Number: I046094
• Molecular Formula: C154H248N42O44S.xC2HF3O2
• Molecular Weight: 3423.94 (free acid)
• Purity: ≥95%

β-Endorphin, equine TFA is an endogenous opioid peptide, which binds at high affinity to both μ/δ opioid receptors. β-Endorphin, equine TFA has analgesic properties[1][2][3][4].
β-Endorphin, equine TFA (0, 0.6, 1.2 and 3 μM) inhibits the striatal dopamine release[4].
β-Endorphin, equine TFA (2 or 20 μg/kg; i.p., once) effects the acquisition and retention in the rat[3].

Reference

[1]. Yahav Dikshtein, et al. β-Endorphin via the Delta Opioid Receptor is a Major Factor in the Incubation of Cocaine Craving. Neuropsychopharmacology. 2013 Nov; 38(12): 2508-2514.

[2]. Niinistö KE, et al. Plasma levels of heat shock protein 72 (HSP72) and beta-endorphin as indicators of stress, pain and prognosis in horses with colic. Vet J. 2010 Apr;184(1):100-4.
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[3]. Izquierdo I. Effects of a low and a high dose of beta-endorphin on acquisition and retention in the rat. Behav Neural Biol. 1980 Dec;30(4):460-4.
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[4]. Loh HH, et al. beta-Endorphin in vitro inhibition of striatal dopamine release. Nature. 1976 Dec 9;264(5586):567-8.
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