For research use only. Not for therapeutic Use.
γ-Hexalactone（Cat No.:I017912） is a naturally occurring gamma-lactone commonly found in ripe fruits. It has been reported to induce DNA damage, potentially affecting cellular processes and genetic stability. Additionally, γ-Hexalactone acts as a substrate for paraoxonase 1 (PON1), an enzyme involved in detoxification processes. The interaction with PON1 suggests a potential role in the metabolism and clearance of xenobiotics.
| Catalog Number | I017912 |
| CAS Number | 695-06-7 |
| Molecular Formula | C₆H₁₀O₂ |
| Purity | ≥95% |
| Target | Endogenous Metabolite |
| Storage | Room Temperature |
| IUPAC Name | 5-ethyloxolan-2-one |
| InChI | InChI=1S/C6H10O2/c1-2-5-3-4-6(7)8-5/h5H,2-4H2,1H3 |
| InChIKey | JBFHTYHTHYHCDJ-UHFFFAOYSA-N |
| SMILES | CCC1CCC(=O)O1 |
| Reference | [1]. E-Nose and GC-MS Reveal a Difference in the Volatile Profiles of White- and Red-Fleshed Peach Fruit. Sensors (Basel). 2018 Mar 2;18(3).<br>[2]. Bianchi T, et al. Investigation of the aroma of commercial peach (Prunus persica L. Batsch) types by Proton Transfer Reaction-Mass Spectrometry (PTR-MS) and sensory analysis. Food Res Int. 2017 Sep;99(Pt 1):133-146.<br>[3]. Shangula S, et al. PON1 increases cellular DNA damage by lactone substrates. Arch Toxicol. 2019 Jul;93(7):2035-2043. |
