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1,2-Dipalmitoyl-sn-glycero-3-phosphocholine (Colfosceril Palmitate)
For research use only. Not for therapeutic Use.
Colfosceril Palmitate(CAT: R057043), also known as 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine, is a vital compound in pharmaceuticals, specifically in the treatment of respiratory distress syndrome (RDS) in premature infants. This synthetic phospholipid derivative emulates natural lung surfactants and is utilized as an exogenous surfactant replacement therapy, effectively reducing surface tension in the lungs’ alveoli. By preventing alveolar collapse, it significantly improves respiratory function in premature infants, making it a critical and life-saving medication in neonatal care.
Catalog Number | R057043 |
CAS Number | 63-89-8 |
Synonyms | (7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]-3,5,9-trioxa-4-phosphapentacosan-1-aminium Inner Salt 4-Oxide; 1,2-Bis(hexadecanoyl)-sn-glycero-3-phosphocholine; 1,2-Bis(palmitoyl)-sn-glycero-3-phosphocholine; L-1,2-Dipalmitoylphosphat |
Molecular Formula | C40H80NO8P |
Purity | ≥95% |
Target | Liposome |
Storage | -20°C |
IUPAC Name | [(2R)-2,3-di(hexadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate |
InChI | InChI=1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1 |
InChIKey | KILNVBDSWZSGLL-KXQOOQHDSA-N |
SMILES | CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCC |