1,​2-​Dipalmitoyl-​sn-​glycero-​3-​phosphocholine (Colfosceril Palmitate)

• CAT Number: R057043
• CAS Number: 63-89-8
• Molecular Formula: C40H80NO8P
• Molecular Weight: 734.053
• Purity: ≥95%
• Synonyms: (7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]-3,5,9-trioxa-4-phosphapentacosan-1-aminium Inner Salt 4-Oxide; 1,2-Bis(hexadecanoyl)-sn-glycero-3-phosphocholine; 1,2-Bis(palmitoyl)-sn-glycero-3-phosphocholine; L-1,2-Dipalmitoylphosphat
• Target: Liposome
• Storage: -20°C
• IUPAC Name: [(2R)-2,3-di(hexadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
• InChI: InChI=1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1
• InChIKey: KILNVBDSWZSGLL-KXQOOQHDSA-N
• SMILES: CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCC

Colfosceril Palmitate(CAT: R057043), also known as 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine, is a vital compound in pharmaceuticals, specifically in the treatment of respiratory distress syndrome (RDS) in premature infants. This synthetic phospholipid derivative emulates natural lung surfactants and is utilized as an exogenous surfactant replacement therapy, effectively reducing surface tension in the lungs’ alveoli. By preventing alveolar collapse, it significantly improves respiratory function in premature infants, making it a critical and life-saving medication in neonatal care.