1-​[(2'-​Carbamoylbiphenyl-​4-​yl) methyl]​-​2-​ethoxybenzimidazole-​7-​carboxylic Acid

• CAT Number: C000614
• CAS Number: 1696392-11-6
• Molecular Formula: C₂₄H₂₁N₃O₄
• Molecular Weight: 415.44
• Purity: ≥95%
• Synonyms: 1-[[2′-(Aminocarbonyl)[1,1′-biphenyl]-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylic Acid
• Solubility: Aqueous Base (Slightly), DMSO (Slightly)
• Appearance: White to Off-White Solid
• Storage: 4°C

1-[(2′-Carbamoylbiphenyl-4-yl)methyl]-2-ethoxybenzimidazole-7-carboxylic Acid (CAT: C000614), also known as Degadant-3, is an intermediate compound used in the synthesis of azilsartan kamedoxomil, which is an angiotensin II receptor blocker. Azilsartan kamedoxomil is used in the treatment of hypertension and related cardiovascular conditions. Degadant-3 plays a crucial role in the preparation of azilsartan kamedoxomil, contributing to the synthesis of this medication.

Reference

Garaga, S., et al.: Org. Process Res. Dev., 19, 514 (2015); Sethi, M. K., et al.: Pharma Chemica, 7, 20 (2015)