1-(2-Mesitylenesulfonyl)-3-nitro-1H-1,2,4-triazole

• CAT Number: R000189
• CAS Number: 74257-00-4
• Molecular Formula: C11H12N4O4S
• Molecular Weight: 296.301
• Purity: ≥95%
• Synonyms: 1-(Mesitylene-2-sulfonyl)-3-nitro-1H-1,2,4-triazole; 3-Nitro-1-[(2,4,6-trimethylphenyl)sulfonyl]-1H-1,2,4-triazole; MSNT
• Storage: -20°C
• IUPAC Name: 3-nitro-1-(2,4,6-trimethylphenyl)sulfonyl-1,2,4-triazole
• InChI: InChI=1S/C11H12N4O4S/c1-7-4-8(2)10(9(3)5-7)20(18,19)14-6-12-11(13-14)15(16)17/h4-6H,1-3H3
• InChIKey: SFYDWLYPIXHPML-UHFFFAOYSA-N
• SMILES: CC1=CC(=C(C(=C1)C)S(=O)(=O)N2C=NC(=N2)[N+](=O)[O-])C

1-(2-Mesitylenesulfonyl)-3-nitro-1H-1,2,4-triazole (CAS 74257-00-4) can be used as a condensing reagent for oligonucleotide synthesis.

Reference

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2.Efimov, Ilya V. "Recent methods for the synthesis of NH-1, 2, 3-triazoles (microreview)." Chemistry of Heterocyclic Compounds 55.1 (2019): 28-30.
3.Chang, Yu-Cheng, Pei-Wen Chao, and Ching-Hsuan Tung. "Sensitive luciferin derived probes for selective carboxypeptidase activity." Bioorganic & medicinal chemistry letters 21.13 (2011): 3931-3934.