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1-(6-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine
For research use only. Not for therapeutic Use.
Org-12962 is a 5-HT 2C receptor agonist potentially for the treatment of depression.
| Catalog Number | M132948 |
| CAS Number | 132834-56-1 |
| Synonyms | 1-(6-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine |
| Molecular Formula | C10H11ClF3N3 |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Storage | -20°C |
| IUPAC Name | 1-[6-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazine |
| InChI | InChI=1S/C10H11ClF3N3/c11-9-7(10(12,13)14)1-2-8(16-9)17-5-3-15-4-6-17/h1-2,15H,3-6H2 |
| InChIKey | QZYYPQAYSFBKPW-UHFFFAOYSA-N |
| SMILES | C1CN(CCN1)C2=NC(=C(C=C2)C(F)(F)F)Cl |
| Reference | </br>1: Halford JC, Harrold JA, Lawton CL, Blundell JE. Serotonin (5-HT) drugs:</br> effects on appetite expression and use for the treatment of obesity. Curr Drug</br> Targets. 2005 Mar;6(2):201-13. Review. PubMed PMID: 15777190.</br>2: Porter RH, Benwell KR, Lamb H, Malcolm CS, Allen NH, Revell DF, Adams DR,</br> Sheardown MJ. Functional characterization of agonists at recombinant human</br> 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells. Br J Pharmacol. 1999</br> Sep;128(1):13-20. PubMed PMID: 10498829; PubMed Central PMCID: PMC1571597.</br>3: Jenck F, Moreau JL, Berendsen HH, Boes M, Broekkamp CL, Martin JR, Wichmann J,</br> Van Delft AM. Antiaversive effects of 5HT2C receptor agonists and fluoxetine in a</br> model of panic-like anxiety in rats. Eur Neuropsychopharmacol. 1998</br> Aug;8(3):161-8. PubMed PMID: 9716307.</br></br> |
