1-(Diphenylmethyl)-4-[(1RS,3E)-4-phenyl-1-[(E)-2-phenylethenyl)-3-buten-1-yl]piperazine

• CAT Number: C000642
• CAS Number: 1199751-98-8
• Molecular Formula: C35H36N2
• Molecular Weight: 484.67
• Purity: ≥95%
• Synonyms: 1-(Diphenylmethyl)-4-[4-phenyl-1-(2-phenylethenyl)-3-buten-1-yl]piperazine; Cinnarizine Impurity D; Cinnarizine EP Impurity D
• Storage: 4°C

1-(Diphenylmethyl)-4-[(1RS,3E)-4-phenyl-1-[(E)-2-phenylethenyl)-3-buten-1-yl]piperazine (CAT: C000642) is an impurity of Cinnarizine, a calcium channel blocker known for its antiallergic, anti-vasoconstricting, and antihistaminic properties. This compound’s mode of action involves blocking calcium channels, leading to vasodilation and reduced histamine-mediated responses. Cinnarizine is commonly used to treat conditions like motion sickness and vertigo.

Reference

Barber, J.H., et al.: Pharmatherapeutica, 2, 401 (1980), Spedding, M., et al.: Arch. Pharmacol., 318, 234 (1982), Morad, et al.: Pharmacol. Res., 35, 177 (1997)