For research use only. Not for therapeutic Use.
1-Methyladenine is a product of alkylation damage in DNA which can be repaired by damage reversal by oxidative demethylation.
| Catalog Number | I046265 |
| CAS Number | 5142-22-3 |
| Synonyms | 1-methyl-7H-purin-6-imine |
| Molecular Formula | C6H7N5 |
| Purity | ≥95% |
| InChI | InChI=1S/C6H7N5/c1-11-3-10-6-4(5(11)7)8-2-9-6/h2-3,7H,1H3,(H,8,9) |
| InChIKey | SATCOUWSAZBIJO-UHFFFAOYSA-N |
| SMILES | CN1C=NC2=C(C1=N)NC=N2 |
| Reference | [1]. Falnes PØ, et al. Repair of 3-methylthymine and 1-methylguanine lesions by bacterial and human AlkB proteins. Nucleic Acids Res. 2004 Dec 1;32(21):6260-7. Print 2004. [2]. Yang H, et al. Effect of 1-methyladenine on double-helical DNA structures. FEBS Lett. 2008 May 14;582(11):1629-33. |
