1-O-(15-carboxypentadecyl)-2-O-acetylglycero-3-phosphorylcholine

• CAT Number: M118755
• CAS Number: 129879-41-0
• Molecular Formula: C26H52NO9P
• Molecular Weight: 553.674
• Purity: ≥95%
• Synonyms: CPAGP;Platelet-activating Factor C-16 Carboxylic Acid
• Storage: -20°C
• IUPAC Name: [(2R)-2-acetyloxy-3-(15-carboxypentadecoxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
• InChI: InChI=1S/C26H52NO9P/c1-24(28)36-25(23-35-37(31,32)34-21-19-27(2,3)4)22-33-20-17-15-13-11-9-7-5-6-8-10-12-14-16-18-26(29)30/h25H,5-23H2,1-4H3,(H-,29,30,31,32)/t25-/m1/s1
• InChIKey: PKDXOBRCEXMRQQ-RUZDIDTESA-N
• SMILES: CC(=O)OC(COCCCCCCCCCCCCCCCC(=O)O)COP(=O)([O-])OCC[N+](C)(C)C

PAF C-<wbr></wbr>16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the “remodeling” and /'de novo/’ pathways. It is a potent mediator of neutrophil migration and the production of reactive oxygen species and IL-<wbr></wbr>6. Pathological processes involving PAF include necrotizing enterocolitis, inflammation, asthma, and allergy. PAF C-<wbr></wbr>16 Carboxylic acid is modified with a carboxylic acid group terminating the C-<wbr></wbr>16 alkyl chain. This provides a convenient site for chemical crosslinking.