For research use only. Not for therapeutic Use.
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (CAT: R000354) is a phospholipid composed of a palmitoyl fatty acid (16:0) at the sn-1 position and an oleoyl fatty acid (18:1) at the sn-2 position, connected to a glycerol backbone through a phosphocholine headgroup. This phospholipid belongs to the phosphatidylcholine class, which is a major constituent of biological membranes. Its unique fatty acid composition contributes to the structural integrity and fluidity of cellular membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is often used in liposome production, allowing researchers to investigate the biophysical properties of lipid bilayers and their interactions with various molecules
| Catalog Number | R000354 |
| CAS Number | 26853-31-6 |
| Synonyms | [R-(Z)]-4-Hydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-3,5,8-trioxa-4-phosphahexacos-17-en-1-aminium 4-Oxide; POPC; |
| Molecular Formula | C42H82NO8P |
| Purity | ≥95% |
| Target | Liposome |
| Storage | -20°C |
| InChIKey | WTJKGGKOPKCXLL-VYOBOKEXSA-N |
| Reference | <br>1. M. Billah and J. Anthes “The regulation and cellular functions of phosphatidylcholinehydrolysis” Biochemistry Journal, Vol. 269 pp. 281-291, 1990<br>2. J. Exton “Signaling through Phosphatidylcholine Breakdown” The Journal of Biological Chemistry, Vol. 265(1) pp. 1-4, 1990<br>3. Z. Li and D. Vance “Phosphatidylcholine and choline homeostasis” Journal of Lipid Research, Vol. 49 pp. 1187-1194, 2008<br>4. T. Yaguchi, T. Nagata, T. Nishizaki “1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine improves cognitive decline by enhancing long-term depression”Behav Brain Res. Vol. 204(1), pp. 129-132, 2009</br></br></br></br> |
