For research use only. Not for therapeutic Use.
10-Cl-BBQ(CAT: I012890) is a potent, high-affinity aryl hydrocarbon receptor (AhR) ligand known for its strong immunosuppressive properties. At nanomolar concentrations, 10-Cl-BBQ effectively promotes the translocation of AhR from the cytosol to the nucleus, initiating transcriptional activation of AhR-regulated reporter genes. This compound is a valuable tool for studying AhR-mediated signaling pathways and their role in immune regulation, inflammation, and toxicological responses. Its high selectivity and efficacy make 10-Cl-BBQ ideal for research in immunology, molecular biology, and pharmacology. Suitable for in vitro and in vivo applications, 10-Cl-BBQ offers researchers a reliable reagent for exploring AhR function and downstream effects.
| CAS Number | 23982-76-5 |
| Synonyms | 7-chloro-3,10-diazapentacyclo[10.7.1.02,10.04,9.016,20]icosa-1(19),2,4(9),5,7,12,14,16(20),17-nonaen-11-one |
| Molecular Formula | C18H9ClN2O |
| Purity | ≥95% |
| IUPAC Name | 7-chloro-3,10-diazapentacyclo[10.7.1.02,10.04,9.016,20]icosa-1(19),2,4(9),5,7,12,14,16(20),17-nonaen-11-one |
| InChI | InChI=1S/C18H9ClN2O/c19-11-7-8-14-15(9-11)21-17(20-14)12-5-1-3-10-4-2-6-13(16(10)12)18(21)22/h1-9H |
| InChIKey | ZJESJVGSDQOZAT-UHFFFAOYSA-N |
| SMILES | C1=CC2=C3C(=C1)C4=NC5=C(N4C(=O)C3=CC=C2)C=C(C=C5)Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
