10-Formyldihydrofolate

• CAT Number: I016405
• CAS Number: 28459-40-7
• Molecular Formula: C20H21N7O7
• Molecular Weight: 471.43
• Purity: 98%
• Synonyms: 10-Formyldihydrofolate
• Target: Endogenous Metabolite
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: (2S)-2-[[4-[(2-amino-4-oxo-7,8-dihydro-3H-pteridin-6-yl)methyl-formylamino]benzoyl]amino]pentanedioic acid
• InChI: InChI=1S/C20H21N7O7/c21-20-25-16-15(18(32)26-20)23-11(7-22-16)8-27(9-28)12-3-1-10(2-4-12)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,13H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,22,25,26,32)/t13-/m0/s1
• InChIKey: UXFQDXABPXWSTK-ZDUSSCGKSA-N
• SMILES: C1C(=NC2=C(N1)N=C(NC2=O)N)CN(C=O)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O

10-Formyldihydrofolate (Cat No.:I016405) is a folate derivative that plays a crucial role in the transfer of one-carbon units during metabolic processes. It is an intermediate in the folate cycle, particularly involved in the synthesis of purines, essential for DNA and RNA synthesis. 10-FDHF is also involved in various enzymatic reactions catalyzed by enzymes like formyltransferases. It is a key molecule in cellular processes such as cell division, growth, and repair. Dysregulation of 10-FDHF levels can contribute to metabolic disorders or impact the effectiveness of certain chemotherapy agents targeting folate metabolism.