[10]-Shogaol

• CAT Number: R072337
• CAS Number: 36752-54-2
• Molecular Formula: C21H32O3
• Molecular Weight: 332.48
• Purity: ≥95%
• Synonyms: (E)-1-(4-hydroxy-3-methoxyphenyl)tetradec-4-en-3-one
• InChI: InChI=1S/C21H32O3/c1-3-4-5-6-7-8-9-10-11-12-19(22)15-13-18-14-16-20(23)21(17-18)24-2/h11-12,14,16-17,23H,3-10,13,15H2,1-2H3/b12-11+
• InChIKey: FADFGCOCHHNRHF-VAWYXSNFSA-N
• SMILES: CCCCCCCCCC=CC(=O)CCC1=CC(=C(C=C1)O)OC

[10]-Shogaol is an antioxidant from Zingiber officinale for human skin cell growth and a migration enhancer. [10]-Shogaol inhibits COX-2 with an IC50 of 7.5 μM and has antiproliferation activity[1][2][3].

Reference

[1]. Chen CY, et al. 10-Shogaol, an antioxidant from Zingiber officinale for skin cell proliferation and migration enhancer. Int J Mol Sci. 2012;13(2):1762-77.
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[2]. van Breemen RB, et al. Cyclooxygenase-2 inhibitors in ginger (Zingiber officinale). Fitoterapia. 2011 Jan;82(1):38-43.
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[3]. Liu CM, et al. Ginger Phytochemicals Inhibit Cell Growth and Modulate Drug Resistance Factors in Docetaxel Resistant Prostate Cancer Cell. Molecules. 2017 Sep 5;22(9). pii: E1477.
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