10,11-dehydro Curvularin

• CAT Number: R066994
• CAS Number: 21178-57-4
• Molecular Formula: C16H18O5
• Molecular Weight: 290.31
• Purity: ≥95%
• Synonyms: α,β-dehydro Curvularin
• Target: Cell Cycle/DNA Damage
• Storage: -20°C
• IUPAC Name: (5S,9E)-13,15-dihydroxy-5-methyl-4-oxabicyclo[10.4.0]hexadeca-1(12),9,13,15-tetraene-3,11-dione
• InChI: InChI=1S/C16H18O5/c1-10-5-3-2-4-6-13(18)16-11(8-15(20)21-10)7-12(17)9-14(16)19/h4,6-7,9-10,17,19H,2-3,5,8H2,1H3/b6-4+/t10-/m0/s1
• InChIKey: AVIRMQMUBGNCKS-RWCYGVJQSA-N
• SMILES: O=C1CC2=C(C(/C=C/CCC[C@H](C)O1)=O)C(O)=CC(O)=C2

10,11-Dehydro Curvularin(CAT: R066994) is a naturally occurring macrocyclic lactone produced by certain fungal species, particularly those of the genus Curvularia. This compound is structurally characterized by a 12-membered ring with a double bond between the 10th and 11th carbon atoms, which distinguishes it from curvularin. 10,11-Dehydro Curvularin has been the subject of research due to its notable biological activities, including anti-inflammatory, antimicrobial, and anticancer properties. It has shown potential in inhibiting the proliferation of cancer cells and modulating immune responses, making it a candidate for further study in drug development. Additionally, its unique structure has sparked interest in synthetic chemistry for the development of new analogs with enhanced bioactivity. The compound’s role in fungal secondary metabolism and its potential applications in medicine make it a valuable subject in natural product research.