For research use only. Not for therapeutic Use.
11-Dehydrocorticosterone is a endogenous corticosteroid. 11-Dehydrocorticosterone can be a source of transcriptionally active glucocorticoid in cardiac myocytes and fibroblasts. 11-Dehydrocorticosterone can increase SGK mRNA expression in cardiac fibroblast[1].
| Catalog Number | R032837 |
| CAS Number | 72-23-1 |
| Synonyms | (8S,9S,10R,13S,14S,17S)-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione |
| Molecular Formula | C21H28O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C21H28O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-16,19,22H,3-8,10-11H2,1-2H3/t14-,15-,16+,19+,20-,21-/m0/s1 |
| InChIKey | FUFLCEKSBBHCMO-KJQYFISQSA-N |
| SMILES | CC12CCC(=O)C=C1CCC3C2C(=O)CC4(C3CCC4C(=O)CO)C |
| Reference | [1]. Sheppard KE, et al. 11Beta-hydroxysteroid dehydrogenase 1 transforms 11-dehydrocorticosterone into transcriptionally active glucocorticoid in neonatal rat heart. Endocrinology. 2002;143(1):198-204. |
