For research use only. Not for therapeutic Use.
11-Deoxy Corticosterone-d8(Cat No.:R047835) is a deuterated form of 11-Deoxy Corticosterone, with eight hydrogen atoms replaced by deuterium. This modification increases its molecular stability, making it an essential tool in endocrinological research, particularly for studying the steroidogenesis pathway and its role in blood pressure regulation and electrolyte balance. It is widely used in studying mineralocorticoid function and its implications in conditions like hypertension and adrenal insufficiency.
Catalog Number | R047835 |
CAS Number | 55487-63-3 |
Synonyms | 21-Hydroxypregn-4-ene-3,20-dione-d8; 11-Deoxycorticosterone-d8; 11-Dehydroxy-?corticosterone-d8; 11-Desoxycorticosterone-d8; 21-Hydroxy-3,20-dioxopregn?-4-ene-d8; 21-Hydroxy-4-pregnane-3,20-dione-d8; 21-Hydroxyprogesterone-d8; Cortexone-d8; DOC-d8; D |
Molecular Formula | C21H30O3 |
Purity | ≥95% |
Storage | -20°C |
IUPAC Name | (8S,9S,10R,13S,14S,17S)-2,2,4,6,6,17-hexadeuterio-17-(2,2-dideuterio-2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one |
InChI | InChI=1S/C21H30O3/c1-20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h11,15-18,22H,3-10,12H2,1-2H3/t15-,16-,17-,18+,20-,21-/m0/s1/i3D2,7D2,11D,12D2,18D |
InChIKey | ZESRJSPZRDMNHY-JRMIWGODSA-N |
SMILES | [2H]C1=C2[C@](CC(C1=O)([2H])[2H])([C@H]3CC[C@]4([C@H]([C@@H]3CC2([2H])[2H])CC[C@]4([2H])C(=O)C([2H])([2H])O)C)C |