11-Keto β-Boswellic Acid

• CAT Number: R053550
• CAS Number: 17019-92-0
• Molecular Formula: C30H46O4
• Molecular Weight: 470.40
• Purity: ≥95%
• Synonyms: (3α,4β)-3-Hydroxy-11-oxours-12-en-23-oic Acid; 3α-Hydroxy-11-oxours-12-en-24-oic Acid; 11-Oxo-β-boswellic Acid; 11-keto-β-Boswellic Acid
• Target: GPCR/G Protein
• Storage: -20°C
• IUPAC Name: (3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bS)-3-hydroxy-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid
• InChI: 1S/C30H46O4/c1-17-8-11-26(3)14-15-28(5)19(23(26)18(17)2)16-20(31)24-27(4)12-10-22(32)30(7,25(33)34)21(27)9-13-29(24,28)6/h16-18,21-24,32H,8-15H2,1-7H3,(H,33,34)/t17-,18+,21-,22-,23+,24-,26-,27+,28-,29-,30-/m1/s1
• InChIKey: YIMHGPSYDOGBPI-BVIVALHHSA-N
• SMILES: C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC(=O)[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@H]([C@]5(C)C(=O)O)O)C)C)[C@@H]2[C@H]1C)C)C

11-Keto β-Boswellic acid (Cat No.:R053550) is a major active component of Boswellia serrata (frankincense) resin. It has demonstrated potent anti-inflammatory, analgesic, and anti-cancer properties. The compound works by inhibiting 5-lipoxygenase, an enzyme involved in the production of pro-inflammatory leukotrienes, which plays a key role in conditions like arthritis, asthma, and inflammatory bowel disease. 11-Keto β-Boswellic acid also shows promise in reducing tumor growth and metastasis, making it a valuable candidate for research in treating inflammation-related diseases and cancers.