11-Keto Budesonide(Mixture of Diastereomers)

• CAT Number: R058655
• CAS Number: 216453-74-6
• Molecular Formula: C25H32O6
• Molecular Weight: 428.52
• Purity: ≥95%
• Synonyms: (16α)-16,17-[Butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione; Budesonide Impurity L (EP)
• Storage: -20°C
• IUPAC Name: (1S,2S,4R,8S,9S,12S,13R)-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-diene-11,16-dione
• InChI: InChI=1S/C25H32O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-17,20-22,26H,4-7,11-13H2,1-3H3/t16-,17-,20+,21?,22+,23-,24-,25+/m0/s1
• InChIKey: NTERSHSWHLAIHV-ADKFLVHOSA-N
• SMILES: CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C4C(=O)CC3(C2(O1)C(=O)CO)C)C

11-Keto budesonide (Cat No.:R058655) is a chemical compound representing a mixture of diastereomers. It is a derivative of budesonide, a corticosteroid used in the treatment of inflammatory conditions like asthma and Crohn’s disease. The presence of the 11-keto group introduces specific reactivity and potential changes in biological activity. The mixture of diastereomers reflects the possible stereoisomers at the 11-keto position. Studying these mixtures helps elucidate structure-activity relationships and their influence on drug efficacy.