For research use only. Not for therapeutic Use.
1,10-phenanthroline hydrochloride monohydrate is a herterocyclic compound with antimycotic and anticancer properties.</br>1,10-phenanthroline HCl monohydrate damages mitochondrial function in fungi by disabling the ability to reduce 2,3,5-triphenyltetrazolium chloride (TTC). 1,10-phenanthroline also inhibits DNA synthesis in cancer cells; however, the mechanism is poorly understood.
| Catalog Number | M084057 |
| CAS Number | 18851-33-7 |
| Molecular Formula | C12H11ClN2O |
| Purity | ≥95% |
| Storage | Desiccate at RT |
| IUPAC Name | 1,10-phenanthroline;hydrate;hydrochloride |
| InChI | InChI=1S/C12H8N2.ClH.H2O/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;;/h1-8H;1H;1H2 |
| InChIKey | NDLHUHRGAIHALB-UHFFFAOYSA-N |
| SMILES | C1=CC2=C(C3=C(C=CC=N3)C=C2)N=C1.O.Cl |
| Reference | Deegan, Carol. /In Vitro Cancer Chemotherapeutic Activity of 1,10-phenanthroline (phen), [Ag2(phen)3(mal)] · 2H2O, [Cu(phen)2(mal)] · 2H2O and [Mn(phen)2(mal)] · 2H2O (malH2 = Malonic Acid) Using Human Cancer Cells./ Cancer Letters 247.2 (2007): 224-33. Web.<br/><br/> |
