11,12-Di-O-methylcarnosol

• CAT Number: I040061
• CAS Number: 25460-12-2
• Molecular Formula: C22H30O4
• Molecular Weight: 358.47
• Purity: ≥95%
• Synonyms: (1R,8S,10S)-3,4-dimethoxy-11,11-dimethyl-5-propan-2-yl-16-oxatetracyclo[6.6.2.01,10.02,7]hexadeca-2,4,6-trien-15-one
• InChI: InChI=1S/C22H30O4/c1-12(2)13-10-14-15-11-16-21(3,4)8-7-9-22(16,20(23)26-15)17(14)19(25-6)18(13)24-5/h10,12,15-16H,7-9,11H2,1-6H3/t15-,16-,22+/m0/s1
• InChIKey: BMUVJFGCCPHXOJ-PONJGIIJSA-N
• SMILES: CC(C)C1=C(C(=C2C(=C1)C3CC4C2(CCCC4(C)C)C(=O)O3)OC)OC

11,12-Di-O-methylcarnosol (Cat No.: I040061) is a methylated derivative of carnosol, a natural diterpenoid with potent antioxidant, anti-inflammatory, and anticancer properties. Found in rosemary and sage, this compound is studied for its role in modulating oxidative stress, apoptosis, and cellular signaling pathways. It has potential applications in cancer, neuroprotection, and metabolic disease research. Its enhanced lipophilicity due to methylation improves bioavailability, making it a valuable tool for in vitro and in vivo studies in drug discovery and natural product research.

Reference

[1]. Nobuji Nakatani, et al. A New Diterpene Lactone, Rosmadial, from Rosemary (Rosmarinus officinalis L.). Agricultural and Biological Chemistry, Volume 47, Issue 2, 1 February 1983, Pages 353-358.