11beta-Prostaglandin E1

For research use only. Not for therapeutic Use.

  • CAT Number: M017581
  • CAS Number: 24570-01-2
  • Molecular Formula: C20H34O5
  • Molecular Weight: 354.487
  • Purity: ≥95%
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<span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">11&beta;-Prostaglandin E<sub>1</sub> (11&beta;-PGE<sub>1</sub>) (CAS 24570-01-2)&nbsp;is an epimerized form of PGE<sub>1</sub> at the C-11 position. 11&beta;-PGE<sub>1</sub> is a less potent isomer of PGE<sub>1</sub>. It is 13% and 3.6% as potent as PGE<sub>1</sub> in contracting the rat uterus and guinea pig ileum, respectively.</span></span>


Catalog Number M017581
CAS Number 24570-01-2
Synonyms

11BETA-PROSTAGLANDIN E1;9-OXO-11BETA-15S-DIHYDROXY-PROST-13E-EN-1-OIC ACID;11β-Prostaglandin E1

Molecular Formula C20H34O5
Purity ≥95%
Target GPCR/G Protein
Storage -20°C
IUPAC Name 7-[(1R,2R,3S)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid
InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19-/m0/s1
InChIKey GMVPRGQOIOIIMI-FZYGRIMQSA-N
SMILES CCCCCC(C=CC1C(CC(=O)C1CCCCCCC(=O)O)O)O
Reference

<p>
<span style="color:#000000;"><span style="font-family:arial,helvetica,sans-serif;"><span style="font-size:12px;">1.<span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">Ramwell, P. W., et al. &quot;Biological activity of synthetic prostaglandins.&quot;&nbsp;</span><i style="font-family: Arial, sans-serif; font-size: 13px; font-variant-ligatures: normal; orphans: 2; widows: 2;">Nature</i><span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">&nbsp;221.5187 (1969): 1251-1253.</span></span></span></span></p>

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