For research use only. Not for therapeutic Use.
Diheptanoyl Thio-<wbr></wbr>PC is a substrate for all phospholipase A<sub>2</sub>s (PLA<sub>2</sub>s) with the exception of cPLA<sub>2</sub> and PAF-<wbr></wbr>acetyl hydrolase (PAF-<wbr></wbr>AH). Interaction of this compound with a PLA<sub>2</sub> results in cleavage of the <em>sn</em>-<wbr></wbr>2 fatty acid generating a free thiol on the lysophospholipid. This free thiol can be detected using chromogenic substrates such as DTNB (Ellman’s reagent) and DTP.
| Catalog Number | R067325 |
| CAS Number | 89019-63-6 |
| Synonyms | Diheptanoyl Thio-PC;1,2-bis(Heptanoylthio)-1,2-dideoxy-sn-glycero-3-phosphorylcholine |
| Molecular Formula | C22H44NO6PS2 |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | [(2S)-2,3-bis(heptanoylsulfanyl)propyl] 2-(trimethylazaniumyl)ethyl phosphate |
| InChI | InChI=1S/C22H44NO6PS2/c1-6-8-10-12-14-21(24)31-19-20(32-22(25)15-13-11-9-7-2)18-29-30(26,27)28-17-16-23(3,4)5/h20H,6-19H2,1-5H3/t20-/m0/s1 |
| InChIKey | LFFIJRJGKBSELO-FQEVSTJZSA-N |
| SMILES | CCCCCCC(=O)SCC(COP(=O)([O-])OCC[N+](C)(C)C)SC(=O)CCCCCC |
