1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE)

For research use only. Not for therapeutic Use.

  • CAT Number: R044737
  • CAS Number: 4004-05-1
  • Molecular Formula: C41H78NO8P
  • Molecular Weight: 744.1
  • Purity: ≥95%
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1,2-<wbr></wbr>Dioleoyl-<wbr></wbr><em>sn</em>-<wbr></wbr>glycero-<wbr></wbr>3-<wbr></wbr>PE (1,2-<wbr></wbr>DOPE) is a synthetic analog of naturally-<wbr></wbr>occurring PE containing 18:1 fatty acids at the <em>sn</em>-<wbr></wbr>1 and <em>sn</em>-<wbr></wbr>2 positions. The compound features the same diacylglycerol stereochemistry as that of the natural compound. 1,2-<wbr></wbr>DOPE can be used as an emulsifier to facilitate DNA-<wbr></wbr>liposome complex transport across membranes. It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-<wbr></wbr>viral method of gene delivery.


Catalog Number R044737
CAS Number 4004-05-1
Synonyms

9-Octadecenoic acid (9Z)-1,1’-[(1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] ester;?9-Octadecenoic acid (9Z)-(1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester; (R)-9-Octadecenoic acid (Z)-1-[[[(2-ami

Molecular Formula C41H78NO8P
Purity ≥95%
Target Liposome
Storage -20°C
InChIKey MWRBNPKJOOWZPW-NYVOMTAGSA-N

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